

Specialized RX
PentraCream™ Anhydrous Hybrid Transdermal Cream Base
PentraCream™ Anhydrous is an elegant, brilliant white transdermal cream base that quickly vanishes upon application. This unique proprietary base offers several advantages over traditional oil/water topicals, which tend to separate or have low API carrying capacity. Specifically designed for hormone replacement or pain management in both men and women, PentraCream™ Anhydrous features a high API carrying matrix, allowing for low volume administration. Its highly functional ingredients enhance solubility and have clinically proven deep skin permeation and penetration results for various pharmaceuticals. This cream promotes the delivery of both lipophilic and hydrophilic APIs, enabling a wide range of topical formulations. It synergistically incorporates allantoin, known for regulating inflammation, stimulating fibroblast proliferation, and enhancing extracellular matrix synthesis, which encourages faster and more effective skin regeneration. Additionally, it includes sodium hyaluronate, which offers many skin benefits, including hydration, elasticity, and overall skin health.
Appearance:
Opaque brilliant white soft shiny cream matrix
Highlights:
- Anhydrous (extended BUD per USP <795>)
- Aw < 0.6 promotes chemical and microbiological stability
- Compatible with botanicals, penetration enhancers, and common wetting agents
- Contains Sodium Hyaluronate and Allantoin for their numerous skin benefits
- Does not contain propylene glycol, which can cause skin irritation
- Elegant white cream base
- Free of dyes, fragrances, BHT, EDTA, urea, parabens, and petrolatum
- Hypoallergenic/non-comedogenic
- Moisturizes and nourishes sensitive skin
- No artificial colors or preservatives
- Paraben-free
- Promotes penetration of compounded preparations
- Readily incorporates both oil-soluble or water-soluble actives
- Salt and heat stable
- Smooth, non-greasy sensory properties, tact-free skin feel
- Suitable for all skin types for dermatology, pain management, wound care, podiatry, veterinary and pediatrics
Additional Information:
MSDS: Available upon request
Technical Data Sheet: See resources
Inquire for bulk pricing
Compounding Chemicals is a licenced TGA Australian supplier.
Our quality management system is certified to AS/NZS ISO 9001:2015.
We hold a TGA Licence to manufacture Therapeutic Goods
(Licence # MI-2019-LI-11427-1).
Spectrum is a FDA approved supplier who adhere to strict Good Manufacturing Practices (cGMP).
GMP Product Logo indicates material is sourced from GMP Certified Manufacturing Facility.
- Spectrum USA stock ships every Friday for next week delivery.
- SpecializedRX USA stock ships alternate weeks.
Call to confirm non-stock ETA.
Local stock. Order now and receive your item in 1-3 business days Australia wide.
All orders over $200 receive free shipping within Australia. Dangerous Goods Shipping Fees apply.
- Spectrum USA stock ships every Friday for next week delivery.
- SpecializedRX USA stock ships alternate weeks.
Call to confirm non-stock ETA.
PentraCream™ Anhydrous Hybrid Transdermal Cream Base
Quality Commitment
Compounding Chemicals is a licenced TGA Australian supplier.
Our quality management system is certified to AS/NZS ISO 9001:2015.
We hold a TGA Licence to manufacture Therapeutic Goods (Licence # MI-2019-LI-11427-1).
Spectrum is a FDA approved supplier who adhere to strict Good Manufacturing Practices (cGMP).
For further enquiries, give us a call (02 9540 2055) or email our friendly sales team (sales@astralscientific.com.au).
For more informationIt's displaying call to confirm stock, how long will delivery take?
Most special orders will take approx. 10-15 business days to arrive. Back order dates on USA stock may vary. Our customer service team will advise you of all lead times once your order is placed.
What is the lead time for USA Stock?
Place your order before 3pm Friday to receive USA Stock items the following week. For all other orders, our friendly customer service team will contact you with a lead time once your order is placed.
What happens if there are two expiry dates available on the website?
The shorter date will be sold at the special price advertised online.
Do you price match or provide bulk quantities?
At Compounding Chemicals, we offer low and competitive prices. If you receive a quote with a lower price than ours, contact our sales team with details of the chemical (product name and code, CAS number) and our team will assist you.
Price match may not be applicable to special orders, terms and conditions apply.
We are also happy to provide special prices on bulk quantities, give us a call (02 9540 2055) or email our sales team (sales@astralscientific.com.au) to enquire.
How much does shipping cost?
All orders over $200 receive free shipping.
For all orders under $200, shipping fees apply:
- New South Wales, South Australia, Victoria and ACT = $35
- Queensland, Northern Territory, Tasmania and Western Australia = $45
- Dangerous Goods Shipping Fees also apply – our customer service
team will advise before processing your order.
Do you provide expiry dates and Certificates of Analysis?
Compounding Chemicals is a TGA licenced supplier. We ship all chemicals with a Certificate of Analysis (COA) and adequate / long expiry on all material. If material is short dated, our customer service team will contact you prior to shipping to confirm. Most items have the expiry date and Certificate of Analysis available on our website for your convenience.